not sure how it looks like in PoE so i can only assume what you want to do from your description.
The standard inventory interface system has only the ability to include all items inside the current characters inventory at once. So you can't separate them there if they have special attributes.
Like often the solution would be lua based: The items a character can hold would need some internal identificarion (name prefix or condition / value) and you need to create an own sytsem in your interface to show only specific items on the left or right (and make them possibly scroll separately) .
a lua script to separate item items from clue items could work like this (pseudo code) :
get current characters items
if name begins with "clue_" put item object into "clues" lua table, if not, put it in "items" lua table.
When opening the interface, get these tables and for each table, iterate through each item and display it on its own interface action area.
When you have 4 slots for clues and 4 slots for items and need scrolling, just iterate through i=startpoint to startpoint +3. Clicking on a "scroll left/right" arrow will change the startpoint -/+ 1 and trigger a rerender of your items.
The rendering of items also need to be done in lua because you cant use the default item system here.
Clicking on an item or clue will then check whats on the current slot position and sets your item at mouse cursor to that item.