Yes it can be scripted via Lua script.
game.AlwaysAllowSkipText = false
You should be able to disable the option in the game tab though as it only affects whether text can be skipped when it is wrapped in cut-scene / hide cursor events. I didn't want to allow left click skipping at all in the game I'm working on so I disabled always allow skip option & I have been wrapping all texts in cut-scene actions so that they can only be skipped via the ESC key. Less likely that the player will unintentionally skip texts & miss anything that way.